Private enterprises offer preimplantation genetic testing with polygenic scores to select embryos with ‘desirable’ potential. In silico simulations using biobank resources show that the selected embryo would rely substantially on the choice of polygenic score method and randomness in score construction, which raises ethical concerns.

中文翻译：

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多基因评分方法中的胚胎选择不一致


私营企业提供具有多基因评分的植入前基因检测，以选择具有“理想”潜力的胚胎。使用生物样本库资源的计算机模拟表明，选定的胚胎将在很大程度上依赖于多基因评分方法的选择和评分构建的随机性，这引发了伦理问题。