Bacterial infections pose considerable health risks, emphasising the critical need for effective and biocompatible antibacterial drugs. Considerably, we developed an efficient antimicrobial system incorporating the combined potential of high-frequency ultrasound and antimicrobial drugs against bacterial infections. A ZnO–kaolinite (Kaol) composite with antibacterial properties was synthesised by growing ZnO on the Kaol nano-clay surface using the co-precipitation method. High-frequency ultrasound efficiently promotes the release of Zn2+, which enhances the antibacterial properties. Furthermore, in-depth in vitro antibacterial studies and bacterial live/dead staining experiments validate the exceptionally high antibacterial performance of the composite. Therefore, owing to the synergistic effects of high-frequency ultrasound and antibacterial properties, the as-prepared novel antibacterial composite is a promising potential substitute for conventional antibacterial agents.

中文翻译：

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纳米粘土负载的 ZnO 抗菌复合材料中 Zn2+ 释放的高频超声调制


细菌感染会带来相当大的健康风险，这凸显了对有效且生物相容性的抗菌药物的迫切需求。相当重要的是，我们开发了一种高效的抗菌系统，结合了高频超声和抗菌药物对抗细菌感染的综合潜力。通过使用共沉淀法在 Kaol 纳米粘土表面生长 ZnO 合成了具有抗菌性能的 ZnO-高岭石 （Kaol） 复合材料。高频超声有效促进 Zn2+ 的释放，从而增强抗菌性能。此外，深入的体外抗菌研究和细菌活/死染色实验验证了复合材料极高的抗菌性能。因此，由于高频超声和抗菌性能的协同作用，所制备的新型抗菌复合材料是传统抗菌剂的潜在替代品。