Recent findings suggest that HIV-1 capsids mimic nuclear transport receptors to engage FG-nucleoporins for entry into host nuclei. In this issue of Cell Host & Microbe, Moschonas et al. report that MX2 forms cytoplasmic condensates comprising FG-nucleoporins resembling nuclear pore complexes to capture viral capsids and hinder their nuclear transport.

中文翻译：

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拟态游戏：类似 NPC 的 MX2 凝聚物捕获病毒


最近的研究结果表明，HIV-1 衣壳模拟核转运受体，与 FG-核孔蛋白结合以进入宿主核。在本期的Cell Host & Microbe中，Moschonas等人报告说，MX2形成细胞质凝聚物，包括FG-核孔蛋白，类似于核孔复合物，以捕获病毒衣壳并阻碍其核运输。