Human papillomavirus (HPV) vaccine is an underutilized tool in cancer prevention. HPV vaccine completion rates in adolescents age 13 to 15 years remain low at 59%. The HPV vaccine can prevent more than 90% of cases of cancer caused by HPV, including cervical, oropharyngeal, anal, penile, vulvar, and vaginal. HPV vaccine is very safe and effective, as demonstrated by numerous large-scale studies. Practice-based strategies can improve vaccination rates, such as having providers give a strong presumptive recommendation for the vaccine, using motivational interviewing for hesitant families, and using electronic health record reminders to prompt providers to offer it, among other interventions. Offering HPV vaccine starting at age 9 years is another evidence-based strategy to improve HPV vaccine completion rates, which has been shown to be acceptable to both providers and parents. [Pediatr Ann. 2024;53(10):e372-e377.].

中文翻译：

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优化对 HPV 相关癌症的保护：揭示 HPV 疫苗接种的好处并克服挑战。


人瘤病毒 （HPV） 疫苗是预防癌症的一种未得到充分利用的工具。13 至 15 岁青少年的 HPV 疫苗接种完成率仍然很低，为 59%。HPV 疫苗可以预防超过 90% 的 HPV 癌症病例，包括宫颈、口咽、肛门、、外阴和阴道。HPV 疫苗非常安全有效，大量大规模研究证明了这一点。基于实践的策略可以提高疫苗接种率，例如让提供者对疫苗给出强有力的推定建议，对犹豫不决的家庭进行动机性访谈，以及使用电子健康记录提醒提示提供者提供疫苗，以及其他干预措施。从 9 岁开始提供 HPV 疫苗是另一种提高 HPV 疫苗完成率的循证策略，这已被证明是提供者和父母都可以接受的。[儿科年鉴 2024;53（10）：e372-e377.]。