BackgroundEndometriosis diagnosis reportedly faces delays of up to 10 years. Despite growing awareness and improved guidelines, information on the current status is limited.ObjectivesTo systematically assess the published evidence on the status of time to diagnosis in individuals with endometriosis, with respect to the definition of time to diagnosis, geographical location and patient characteristics.Search StrategyMEDLINE (via PubMed) and Embase were searched for publications reporting time to diagnosing endometriosis since 2018. No restrictions to population or comparators were applied. All publications were screened by two independent reviewers.Selection CriteriaSearch results were limited to primary publications of randomised controlled trials, non‐randomised trials and observational studies. Case reports, secondary publications and grey literature were excluded. No restrictions were made regarding language, provided that an English title and abstract were available.Data Collection and AnalysisPublications were assessed with respect to time to diagnosis, diagnostic methods, study type, study country and potential bias.Main ResultsThe 17 publications eligible for inclusion in this literature review were all observational studies. The publications reported diagnosis times between 0.3 and 12 years, with variations depending on the definition of time to diagnosis (overall, primary, or clinical), geographical location and characteristics of the included study population. Evidence was of poor to good quality overall.ConclusionsDiagnostic delay is still present, primarily driven by physicians, and this review underscores the need for standardised definitions, increased awareness and targeted diagnostic interventions.

中文翻译：

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子宫内膜异位症的诊断时间：现状、挑战和区域特征——系统文献综述


背景据报道，子宫内膜异位症的诊断面临长达 10 年的延迟。尽管意识不断提高，指南也得到了改进，但有关当前状态的信息有限。目的系统评价已发表的子宫内膜异位症患者诊断时间状况的证据，包括诊断时间的定义、地理位置和患者特征。检索 StrategyMEDLINE （通过 PubMed） 和 Embase 检索了自 2018 年以来报告诊断子宫内膜异位症时间的出版物。对人群或对照对象没有限制。所有出版物均由两名独立评价员筛选。纳入排除标准搜索结果仅限于随机对照试验、非随机试验和观察性研究的原始出版物。病例报告、二次出版物和灰色文献被排除在外。对语言没有限制，只要有英文标题和摘要即可。数据收集与分析根据诊断时间、诊断方法、研究类型、研究国家和潜在偏倚对出版物进行评估。主要结果符合本文献综述纳入条件的 17 篇出版物均为观察性研究。这些出版物报告的诊断时间在 0.3 至 12 年之间，根据诊断时间的定义（总体、原发性或临床）、地理位置和纳入研究人群的特征而有所不同。证据总体质量为差到好。结论诊断延迟仍然存在，主要由医生驱动，本综述强调了标准化定义、提高认识和有针对性的诊断干预的必要性。