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Outer Retinal Thinning is Associated With Brain Atrophy in Early Age-Related Macular Degeneration
American Journal of Ophthalmology ( IF 4.1 ) Pub Date : 2024-10-05 , DOI: 10.1016/j.ajo.2024.09.033 Yu Jiang, Thomas Swain, Nayoon Gim, Marian Blazes, Christine Mac Donald, Ariel Rokem, Julia P. Owen, Niranjan Balu, Mark E. Clark, Lukas Goerdt, Gerald McGwin, David Hunt, Christine A. Curcio, Swati Rane Levendovszky, Emily H. Trittschuh, Cynthia Owsley, Cecilia S. Lee
American Journal of Ophthalmology ( IF 4.1 ) Pub Date : 2024-10-05 , DOI: 10.1016/j.ajo.2024.09.033 Yu Jiang, Thomas Swain, Nayoon Gim, Marian Blazes, Christine Mac Donald, Ariel Rokem, Julia P. Owen, Niranjan Balu, Mark E. Clark, Lukas Goerdt, Gerald McGwin, David Hunt, Christine A. Curcio, Swati Rane Levendovszky, Emily H. Trittschuh, Cynthia Owsley, Cecilia S. Lee
Both retinal changes and age-related macular degeneration (AMD) have been shown to be associated with Alzheimer's disease and related dementias (ADRD). In AMD, the outer retina is impacted significantly and early, but little is known about its association with cognition or changes in brain morphometry. This study investigates the relationship between retinal and brain morphometry in older adults with early and intermediate AMD.
中文翻译:
视网膜外层变薄与早期年龄相关性黄斑变性的脑萎缩有关
视网膜变化和年龄相关性黄斑变性 (AMD) 已被证明与阿尔茨海默病和相关痴呆症 (ADRD) 有关。在 AMD 中,外视网膜受到显著的早期影响,但对其与认知或大脑形态测量变化的关系知之甚少。本研究调查了患有早期和中期 AMD 的老年人视网膜和大脑形态测量之间的关系。
更新日期:2024-10-05
中文翻译:
视网膜外层变薄与早期年龄相关性黄斑变性的脑萎缩有关
视网膜变化和年龄相关性黄斑变性 (AMD) 已被证明与阿尔茨海默病和相关痴呆症 (ADRD) 有关。在 AMD 中,外视网膜受到显著的早期影响,但对其与认知或大脑形态测量变化的关系知之甚少。本研究调查了患有早期和中期 AMD 的老年人视网膜和大脑形态测量之间的关系。