Background Falls have high socioeconomic costs. Information and communication technologies may support provision and monitoring of multisensory (MSR) physiotherapy programmes. The HOLOBalance platform used augmented reality holograms to provide patient-centred, individualised MSR. Objectives To determine the platform’s safety, acceptability and feasibility, investigate functional gait and dynamic balance benefits and provide data for a definitive trial. Design and setting Single-blinded pilot randomised controlled feasibility study. Interventions were conducted at clinical sites or participants’ homes in three European countries. Participants Community-dwelling older adults (median age 73 years; 64.2% female) at risk of falls were enrolled (May 2020-August 2021). Methods Participants were randomised to an 8-week clinic or home-based telerehabilitation MSR or OTAGO (control group) programme. Compliance, satisfaction, and adverse events determined feasibility. Clinical outcomes, assessed (blinded) within one-week prior to and post-intervention, included functional gait assessment (FGA), Mini BESTest and cognitive function. Results Randomisation to completion rate was 76.15% with 109 participants recruited (n = 289 screened). Drop-out rate was similar between groups. Adverse events were reported (n = 3) in the control group. Sixty-nine percent would recommend the HOLOBalance intervention. Findings were similar for the home and clinic-based arms of each intervention; data was combined for analysis. FGA (95%CI [1.63, 4.19]) and Mini-BESTest (95%CI [1.46, 3.93]) showed greater improvement in the HOLOBalance group with a clinically meaningful change of 4/30 noted for the FGA. Conclusions HOLObalance was feasible to implement and acceptable to older adults at risk of falls, with FGA and Mini-BEST improvements exceeding those for the OTAGO programme. A definitive trial is warranted.

中文翻译：

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与有跌倒风险的老年人的标准护理相比，HOLObalance 远程康复系统的可行性和可接受性：HOLOBalance 评估员盲法试点随机对照研究


背景 瀑布具有很高的社会经济成本。信息和通信技术可能支持多感官 （MSR） 物理治疗计划的提供和监测。HOLOBalance 平台使用增强现实全息图来提供以患者为中心的个性化 MSR。目标 确定平台的安全性、可接受性和可行性，研究功能步态和动态平衡的好处，并为最终试验提供数据。设计和设置 单盲试点随机对照可行性研究。干预在 3 个欧洲国家的临床地点或参与者家中进行。参与者 有跌倒风险的社区老年人（中位年龄 73 岁;64.2% 为女性）被纳入（2020 年 5 月至 2021 年 8 月）。方法 参与者被随机分配到为期 8 周的诊所或家庭远程康复 MSR 或 OTAGO （对照组） 计划。依从性、满意度和不良事件决定了可行性。干预前后 1 周内评估 （盲法） 的临床结局包括功能步态评估 （FGA） 、 Mini BESTest 和认知功能。结果随机化至完成率为 76.15%，招募了 109 名参与者 （n = 289 筛选）。各组间的退出率相似。对照组报告了不良事件 （n = 3）。69% 的人会推荐 HOLOBalance 干预。每种干预措施的家庭组和诊所组的结果相似;合并数据进行分析。FGA （95% CI [1.63， 4.19]） 和 Mini-BESTest （95% CI [1.46， 3.93]） 显示 HOLOBalance 组的改善更大，FGA 的临床意义变化为 4/30。 结论 HOLObalance 实施是可行的，并且对于有跌倒风险的老年人来说是可以接受的，FGA 和 Mini-BEST 的改善超过了 OTAGO 计划。需要进行确定性试验。