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Plasma and CSF neurofilament light chain distinguish neurodegenerative from primary psychiatric conditions in a clinical setting
Alzheimer's & Dementia ( IF 13.0 ) Pub Date : 2024-10-06 , DOI: 10.1002/alz.14278
Dhamidhu Eratne, Matthew J. Y. Kang, Courtney Lewis, Christa Dang, Charles B. Malpas, Michael Keem, Jasleen Grewal, Vladimir Marinov, Amy Coe, Cath Kaylor-Hughes, Thomas Borchard, Chhoa Keng-Hong, Alexandra Waxmann, Burcu Saglam, Tomas Kalincik, Richard Kanaan, Wendy Kelso, Andrew Evans, Sarah Farrand, Samantha Loi, Mark Walterfang, Christiane Stehmann, Qiao-Xin Li, Steven Collins, Colin L. Masters, Alexander F. Santillo, Henrik Zetterberg, Kaj Blennow, Samuel F. Berkovic, Dennis Velakoulis

People with neurodegenerative disorders (ND) frequently face diagnostic delay and misdiagnosis. We investigated blood and cerebrospinal fluid (CSF) neurofilament light chain (NfL) to distinguish ND from primary psychiatric disorders (PPD), a common challenge in clinical settings.

中文翻译:


血浆和脑脊液神经丝轻链在临床环境中区分神经退行性疾病和原发性精神疾病



神经退行性疾病 (ND) 患者经常面临诊断延迟和误诊。我们研究了血液和脑脊液 (CSF) 神经丝轻链 (NfL),以区分 ND 和原发性精神疾病 (PPD),后者是临床环境中的常见挑战。
更新日期:2024-10-06
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