Purpose: Over 50% of people with serious mental illness (SMI) smoke cigarettes. This study evaluated whether tobacco use impacted weight loss outcomes during a peer-led healthy lifestyle intervention (PGLB) for people with SMI living in permanent supportive housing (PSH). Method: Data from an effectiveness trial of PGLB examined whether baseline tobacco use moderated the effectiveness of the intervention compared to usual care (UC) in helping participants lose weight. PGLB was conducted in three sites in two U.S. cities between 2015 and 2018. Results: 63% of participants were current cigarette smokers. Smoking did not moderate the effect of the intervention. However, baseline tobacco use predicted greater weight loss ( b = −4.1, p = .022) over the course of the trial, regardless of treatment group. Discussion: Tobacco use was a significant driver of weight loss for study participants. Findings have implications for offering tobacco cessation treatment during healthy lifestyle interventions for people with SMI.

中文翻译：

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对生活在永久支持性住房中的严重精神疾病患者进行同伴主导的健康生活方式干预期间吸烟对减肥的影响


目的：超过 50% 的患有严重精神疾病 (SMI) 的人吸烟。本研究评估了在同伴主导的健康生活方式干预 (PGLB) 中，对居住在永久支持性住房 (PSH) 的 SMI 患者来说，烟草使用是否会影响减肥结果。方法：来自 PGLB 有效性试验的数据检查了与常规护理 (UC) 相比，基线烟草使用是否会调节干预措施在帮助参与者减肥方面的有效性。 2015 年至 2018 年间，PGLB 在美国两个城市的三个地点进行。结果：63% 的参与者是当前吸烟者。吸烟并没有减弱干预的效果。然而，无论治疗组如何，基线烟草使用预测试验过程中体重减轻幅度更大（b = -4.1，p = .022）。讨论：烟草使用是研究参与者体重减轻的重要驱动因素。研究结果对于在健康生活方式干预期间为 SMI 患者提供戒烟治疗具有重要意义。