The dorsal vagal complex contains three structures: the area postrema, the nucleus tractus solitarii, and the dorsal motor nucleus of the vagus. These structures are tightly linked, both anatomically and functionally, and have important yet distinct roles in not only conveying peripheral bodily signals to the rest of the brain but in the generation of behavioral and physiological responses. Reports on the new discoveries in these structures were highlights of the symposium. In this outlook, we focus on the roles of the area postrema in mediating brain–body interactions and its potential utility as a therapeutic target, especially in cancer cachexia.

中文翻译：

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极后区：脑-体相互作用的关键介质


迷走神经背侧复合体包含三个结构：极后区、孤束核和迷走神经背侧运动核。这些结构在解剖学和功能上都紧密相连，不仅在将外周身体信号传达到大脑的其他部分，而且在行为和生理反应的产生中具有重要而独特的作用。关于这些结构中新发现的报告是研讨会的亮点。在本展望中，我们重点关注极后区域在介导脑-身体相互作用中的作用及其作为治疗靶点的潜在效用，尤其是在癌症恶病质中。