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Bridging brain and body in cancer
Genes & Development ( IF 7.5 ) Pub Date : 2024-09-01 , DOI: 10.1101/gad.352300.124 Michael Cross, Andrew Dillin, Thales Papagiannakopoulos
Genes & Development ( IF 7.5 ) Pub Date : 2024-09-01 , DOI: 10.1101/gad.352300.124 Michael Cross, Andrew Dillin, Thales Papagiannakopoulos
Recent work has highlighted the central role the brain–body axis plays in not only maintaining organismal homeostasis but also coordinating the body's response to immune and inflammatory insults. Here, we discuss how science is poised to address the many ways that our brain is directly involved with disease. In particular, we feel that combining cutting-edge tools in neuroscience with translationally relevant models of cancer will be critical to understanding how the brain and tumors communicate and modulate each other's behavior.
中文翻译:
在癌症中架起大脑和身体的桥梁
最近的工作强调了脑-身体轴在维持机体稳态和协调身体对免疫和炎症损伤的反应方面发挥的核心作用。在这里,我们讨论了科学如何解决我们的大脑与疾病直接相关的多种方式。特别是,我们认为将神经科学的尖端工具与癌症的转化相关模型相结合,对于理解大脑和肿瘤如何交流和调节彼此的行为至关重要。
更新日期:2024-09-01
中文翻译:
在癌症中架起大脑和身体的桥梁
最近的工作强调了脑-身体轴在维持机体稳态和协调身体对免疫和炎症损伤的反应方面发挥的核心作用。在这里,我们讨论了科学如何解决我们的大脑与疾病直接相关的多种方式。特别是,我们认为将神经科学的尖端工具与癌症的转化相关模型相结合,对于理解大脑和肿瘤如何交流和调节彼此的行为至关重要。