The world of cancer science is moving toward a paradigm shift in making connections with neuroscience. After decades of research on genetic instability and mutations or on the tumor microenvironment, emerging evidence suggests that a malignant tumor is able to hijack and use the brain and its network of peripheral and central neurons as disrupters of homeostasis in the body. Whole-body homeostasis requires brain–body circuits to maintain survival and health via the processes of interoception, immunoception, and nociception. It is now likely that cancer disturbs physiological brain–body communication in making bidirectional brain tumor connections.

中文翻译：

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 多么美妙的世界啊！


癌症科学世界正在朝着与神经科学建立联系的范式转变发展。经过数十年对遗传不稳定性和突变或肿瘤微环境的研究，新出现的证据表明，恶性肿瘤能够劫持并利用大脑及其外周和中枢神经元网络作为体内平衡的破坏者。全身稳态需要脑-体回路通过内感受、免疫感受和伤害感受过程来维持生存和健康。现在，癌症很可能在建立双向脑肿瘤连接时干扰了生理脑-身体通讯。