Neural reflexes occupy a central role in physiological homeostasis. The vagus nerve is a major conduit for transmitting afferent and efferent signals in homeostatic reflex arcs between the body and the brain. Recent advances in neuroscience, immunology, and physiology have revealed important vagus nerve mechanisms in suppressing inflammation and treating rheumatoid arthritis and other autoimmune conditions. Numerous clinical trials indicate that there is significant benefit to vagus nerve stimulation therapy. Although many questions are still unanswered, it will be important, even necessary, to pursue answers that will be useful in guiding interventions to modulate immunological and physiological homeostasis.

中文翻译：

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巩固神经免疫反射的作用：稳态免疫网络中传入、中枢和传出信号的特异性


神经反射在生理稳态中起着核心作用。迷走神经是在身体和大脑之间的稳态反射弧中传递传入和传出信号的主要管道。神经科学、免疫学和生理学的最新进展揭示了迷走神经在抑制炎症和治疗类风湿性关节炎和其他自身免疫性疾病方面的重要机制。大量临床试验表明，迷走神经刺激疗法有显着益处。尽管许多问题仍未得到解答，但寻求有助于指导干预免疫和生理稳态的答案是重要的，甚至是必要的。