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Ubiquitous ubiquitin: From bacteria to eukaryotes
Structure ( IF 4.4 ) Pub Date : 2024-10-03 , DOI: 10.1016/j.str.2024.09.002 Mohit Misra, Ivan Ðikić
Structure ( IF 4.4 ) Pub Date : 2024-10-03 , DOI: 10.1016/j.str.2024.09.002 Mohit Misra, Ivan Ðikić
In a recent issue of Nature, Chambers et al.1 combined bioinformatics, biochemistry, and X-ray crystallography to uncover the presence of a ubiquitin-like machinery in bacteria, which was believed to be unique to archaea and eukaryotes. This study highlights the prevalence of a ubiquitin-like system in bacteria that was later adopted by the eukaryotes for various purposes such as protein degradation.
中文翻译:
无处不在的泛素:从细菌到真核生物
在最近一期的《自然》杂志上,钱伯斯等人。 1结合了生物信息学、生物化学和 X 射线晶体学,揭示了细菌中存在的类泛素机制,这种机制被认为是古细菌和真核生物所独有的。这项研究强调了细菌中普遍存在的类泛素系统,该系统后来被真核生物用于蛋白质降解等各种目的。
更新日期:2024-10-03
中文翻译:
无处不在的泛素:从细菌到真核生物
在最近一期的《自然》杂志上,钱伯斯等人。 1结合了生物信息学、生物化学和 X 射线晶体学,揭示了细菌中存在的类泛素机制,这种机制被认为是古细菌和真核生物所独有的。这项研究强调了细菌中普遍存在的类泛素系统,该系统后来被真核生物用于蛋白质降解等各种目的。