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Clozapine monitoring requirements: is it time for an update?
The British Journal of Psychiatry ( IF 8.7 ) Pub Date : 2024-10-03 , DOI: 10.1192/bjp.2024.150 Emilio Fernandez-Egea, Robert A. McCutcheon
中文翻译:
氯氮平监测要求:是时候更新了吗?
更新日期:2024-10-03
The British Journal of Psychiatry ( IF 8.7 ) Pub Date : 2024-10-03 , DOI: 10.1192/bjp.2024.150 Emilio Fernandez-Egea, Robert A. McCutcheon
Oloyede and colleagues advocate for updating haematological monitoring requirements for clozapine, arguing that current protocols overestimate the risk of clozapine-induced agranulocytosis. Their research suggests that stringent monitoring may unnecessarily limit access to clozapine, a crucial treatment for resistant schizophrenia. The editorial supports calls for international consensus to carefully weigh the pros and cons of relaxing monitoring guidelines while ensuring comprehensive care for patients.
中文翻译:
氯氮平监测要求:是时候更新了吗?
Oloyede 及其同事主张更新氯氮平的血液学监测要求,认为目前的方案高估了氯氮平诱导的粒细胞缺乏症的风险。他们的研究表明,严格的监测可能会不必要地限制氯氮平的获得,氯氮平是治疗耐药性精神分裂症的关键方法。社论支持呼吁国际共识,在确保对患者进行全面护理的同时,仔细权衡放宽监测指南的利弊。