Immune recognition of cancers can be inhibited if the molecules that present cancer cell-specific antigens are disrupted. We have developed a tool that can detect four different types of disruption. Overall, we find that both genetic and non-genetic disruption of these molecules is common in lung and breast tumors.

中文翻译：

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遗传性和非遗传性 HLA 破坏在肺和乳腺肿瘤中广泛存在


如果呈递癌细胞特异性抗原的分子被破坏，则可抑制对癌症的免疫识别。我们开发了一种工具，可以检测四种不同类型的中断。总体而言，我们发现这些分子的遗传和非遗传破坏在肺肿瘤和乳腺肿瘤中都很常见。