Invasive migration requires cells to break through extracellular matrix barriers, which is an energy-expensive process. In this issue, Park et al. (https://doi.org/10.1083/jcb.202402035) highlight the importance of biosynthesis of fatty acids, phospholipids, and isoprenoids in driving invasive migration of the Caenorhabditis elegans anchor cell through a basement membrane barrier during development.

中文翻译：

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脂质合成引领侵入性迁移。


侵袭性迁移需要细胞突破细胞外基质屏障，这是一个耗能的过程。在本期中，Park 等人。 (https://doi.org/10.1083/jcb.202402035) 强调了脂肪酸、磷脂和类异戊二烯的生物合成在驱动秀丽隐杆线虫锚细胞在发育过程中通过基底膜屏障侵袭性迁移的重要性。