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Association of Multiple Nonhypertrophic Cardiomyopathy–Related Genetic Variants and Outcomes in Patients With Hypertrophic Cardiomyopathy
JACC: Heart Failure ( IF 10.3 ) Pub Date : 2024-09-25 , DOI: 10.1016/j.jchf.2024.08.005 Takashi Hiruma MD, Shunsuke Inoue MD PhD, Zhehao Dai MD PhD MPH, Seitaro Nomura MD PhD, Toru Kubo MD PhD, Kenta Sugiura MD PhD, Atsushi Suzuki MD PhD, Takeshi Kashimura MD PhD, Shouji Matsushima MD PhD, Takanobu Yamada MD PhD, Takashige Tobita MD PhD, Manami Katoh MD PhD, Toshiyuki Ko MD PhD, Masamichi Ito MD PhD, Junichi Ishida MD PhD, Eisuke Amiya MD PhD, Masaru Hatano MD PhD, Norifumi Takeda MD PhD, Eiki Takimoto MD PhD, Hiroshi Akazawa MD PhD, Hiroyuki Morita MD PhD, Junichi Yamaguchi MD PhD, Takayuki Inomata MD PhD, Hiroyuki Tsutsui MD PhD, Hiroaki Kitaoka MD PhD, Hiroyuki Aburatani MD PhD, Norihiko Takeda MD PhD, Issei Komuro MD PhD
JACC: Heart Failure ( IF 10.3 ) Pub Date : 2024-09-25 , DOI: 10.1016/j.jchf.2024.08.005 Takashi Hiruma MD, Shunsuke Inoue MD PhD, Zhehao Dai MD PhD MPH, Seitaro Nomura MD PhD, Toru Kubo MD PhD, Kenta Sugiura MD PhD, Atsushi Suzuki MD PhD, Takeshi Kashimura MD PhD, Shouji Matsushima MD PhD, Takanobu Yamada MD PhD, Takashige Tobita MD PhD, Manami Katoh MD PhD, Toshiyuki Ko MD PhD, Masamichi Ito MD PhD, Junichi Ishida MD PhD, Eisuke Amiya MD PhD, Masaru Hatano MD PhD, Norifumi Takeda MD PhD, Eiki Takimoto MD PhD, Hiroshi Akazawa MD PhD, Hiroyuki Morita MD PhD, Junichi Yamaguchi MD PhD, Takayuki Inomata MD PhD, Hiroyuki Tsutsui MD PhD, Hiroaki Kitaoka MD PhD, Hiroyuki Aburatani MD PhD, Norihiko Takeda MD PhD, Issei Komuro MD PhD
Approximately 10% of hypertrophic cardiomyopathy (HCM) patients have left ventricular systolic dysfunction (end-stage HCM) leading to severe heart-failure; however, risk stratification to identify patients at risk of progressing to end-stage HCM remains insufficient.
中文翻译：
肥厚型心肌病患者多发性非肥厚型心肌病相关遗传变异与结局的关联
大约 10% 的肥厚型心肌病 （HCM） 患者有左心室收缩功能障碍（终末期 HCM），导致严重心力衰竭;然而，用于识别有进展至终末期 HCM 风险的患者的风险分层仍然不足。
更新日期：2024-09-25
中文翻译：
肥厚型心肌病患者多发性非肥厚型心肌病相关遗传变异与结局的关联
大约 10% 的肥厚型心肌病 （HCM） 患者有左心室收缩功能障碍（终末期 HCM），导致严重心力衰竭;然而，用于识别有进展至终末期 HCM 风险的患者的风险分层仍然不足。
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