Circulating tumour cells from primary carcinomas may reach the brain and establish metastases. In the brain parenchyma, tumour cells initiate extensive interactions with resident astrocytes, microglia and neurons, forming a niche where tumour cells can thrive. A new study reveals a previously unknown type of astrocyte–tumour cell interaction.

中文翻译：

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星形胶质细胞是脑转移的促成因素


来自原发性癌的循环肿瘤细胞可能到达大脑并建立转移。在脑实质中，肿瘤细胞与常驻星形胶质细胞、小胶质细胞和神经元展开广泛的相互作用，形成肿瘤细胞可以茁壮成长的生态位。一项新的研究揭示了一种以前未知的星形胶质细胞-肿瘤细胞相互作用类型。