The reaction of 2-hydroxyoctadecanoyl chloride (2) and anthranilic acid gave 2-(1-hydroxyheptadecyl)-4H-3,1-benzoxazin-4-one (3) which was used as starting material to synthesize some condensed and noncondensed heterocyclic compounds by reaction with nitrogen nucleophiles (e.g., hydrazine hydrate, and formamide). Subsequent reaction of the synthetic products with different amounts of propylene oxide gave a novel group of nonionic compounds having a double function as antimicrobial and surface active agents which may be useful in the manufacture of drugs, cosmetics, pesticides or as antibacterial and/or antifungal. The surface active properties such as surface and interfacial tensions, cloud point, foaming height, wetting time, and emulsification power were determined. The antimicrobial and biodegradability were also screened.

中文翻译：

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缩合和非缩合杂环化合物的合成与评价

2- hydroxyoctadecanoyl氯（反应2）和邻氨基苯甲酸，得到2-（1- hydroxyheptadecyl）-4- ħ -3,1-苯并恶嗪-4-酮（3将其用作起始材料来合成一些冷凝和未冷凝的杂环）通过与氮亲核试剂反应（例如，水合肼和甲酰胺）。合成产物与不同量的环氧丙烷的随后反应产生了具有抗微生物和表面活性剂双重功能的新型非离子化合物，其可用于制造药物，化妆品，杀虫剂或用作抗细菌和/或抗真菌剂。测定了表面活性性质，例如表面和界面张力，浊点，发泡高度，润湿时间和乳化能力。还筛选了抗微生物和生物降解性。