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Insights into reproduction-regulating NOD-like receptors
Nature Structural & Molecular Biology ( IF 12.5 ) Pub Date : 2024-09-27 , DOI: 10.1038/s41594-024-01383-7 Inga V. Hochheiser, Matthias Geyer
Nature Structural & Molecular Biology ( IF 12.5 ) Pub Date : 2024-09-27 , DOI: 10.1038/s41594-024-01383-7 Inga V. Hochheiser, Matthias Geyer
An understudied subset of NOD-like receptors are involved in the reproductive system, and their dysfunction can cause infertility. The recently obtained structures of the core subcortical maternal complex assembled around one of them, NLRP5, provide important insight into this building block of early embryo cytoplasmic lattices.
中文翻译:
了解生殖调节 NOD 样受体
一个研究不足的 NOD 样受体子集参与生殖系统,它们的功能障碍会导致不孕。最近获得的围绕其中一个 NLRP5 组装的核心皮质下母体复合体的结构为早期胚胎细胞质晶格的这一构建块提供了重要的见解。
更新日期:2024-09-27
中文翻译:
了解生殖调节 NOD 样受体
一个研究不足的 NOD 样受体子集参与生殖系统,它们的功能障碍会导致不孕。最近获得的围绕其中一个 NLRP5 组装的核心皮质下母体复合体的结构为早期胚胎细胞质晶格的这一构建块提供了重要的见解。