Childhood Sexual Abuse (CSA) poses a significant risk to mental health, especially among adolescents. This systematic review and meta-analysis investigates the association between CSA and adolescent psychopathology. Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 guidelines, we conducted an extensive search across multiple databases, including PubMed, Scopus, PsycINFO, Science Direct, Embase, and ProQuest, resulting in 27,207 observational studies. From this pool, 87 studies ( n: 189,393) were included in the qualitative synthesis and 78 studies were included in meta-analysis, discussing CSA and adolescent’s psychopathology Random effect model with Cohen’s d values were used to analyze data. To assess publication bias, funnel plots, Egger’s regression test, and the fill and trim method were employed, with no significant bias found. The results indicated a positive correlation between CSA and adolescent psychopathology, for example, depression, anxiety, PTSD, suicidal ideation, nonsuicidal self-injury, anger, substance use, and sexrelated behaviors (Pooled association: 0.13–0.25, 95% CI [0.04, 0.28]). Subgroup analysis showed the strongest association in clinical samples. Furthermore, the moderator analysis suggested minimal influence of study-level variables, as well as men showing higher levels of anger and suicidal ideation. The positive correlation between CSA and psychopathological outcomes highlights the detrimental effects of CSA on adolescents’ mental health. To mitigate these effects, increased awareness, prevention efforts, and targeted interventions are essential.

中文翻译：

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童年性虐待与青少年精神病理学的关联：系统回顾和荟萃分析


儿童期性虐待 (CSA) 对心理健康构成重大风险，尤其是青少年。这项系统回顾和荟萃分析调查了 CSA 与青少年精神病理学之间的关联。根据 2020 年系统评价和荟萃分析的首选报告项目指南，我们对多个数据库进行了广泛的搜索，包括 PubMed、Scopus、PsycINFO、Science Direct、Embase 和 ProQuest，得出 27,207 项观察性研究。从这个库中，87 项研究（n：189,393）被纳入定性综合，78 项研究被纳入荟萃分析，讨论 CSA 和青少年的精神病理学。使用具有 Cohen d 值的随机效应模型来分析数据。为了评估发表偏倚，采用了漏斗图、Egger 回归测试以及填充和修剪方法，未发现显着偏倚。结果表明，CSA 与青少年精神病理学之间呈正相关，例如抑郁、焦虑、PTSD、自杀意念、非自杀性自残、愤怒、物质使用和性相关行为（合并关联：0.13–0.25，95% CI [0.04] ，0.28]）。亚组分析显示临床样本中的关联性最强。此外，调节分析表明，研究水平变量以及男性表现出较高水平的愤怒和自杀意念的影响最小。 CSA 与心理病理结果之间的正相关性凸显了 CSA 对青少年心理健康的有害影响。为了减轻这些影响，提高认识、预防工作和有针对性的干预措施至关重要。