Nature Reviews Chemistry ( IF 38.1 ) Pub Date : 2024-09-26 , DOI: 10.1038/s41570-024-00650-x Kane A. C. Bastick, Dean D. Roberts, Allan J. B. Watson
Organoboron chemistry has become a cornerstone of modern synthetic methodology. Most of these reactions use an organoboron starting material that contains just one C(sp2)–B or C(sp3)–B bond; however, there has been a recent and accelerating trend to prepare multiborylated alkanes that possess two or more C(sp3)–B bonds. This is despite a lack of general reactivity, meaning many of these compounds currently offer limited downstream synthetic value. This Review summarizes recent advances in the exploration of multiborylated alkanes, including a discussion on how these products may be elaborated in further synthetic manipulations.
中文翻译:
多重硼酸化烷烃的当前用途和未来潜力
有机硼化学已成为现代合成方法的基石。这些反应中的大多数使用仅包含一个 C(sp2)–B 或 C(sp3)–B 键的有机硼起始材料;然而,最近出现了一种加速的趋势,即制备具有两个或多个 C(sp3)-B 键的多重硼酸化烷烃。尽管缺乏一般反应性,这意味着这些化合物中的许多化合物目前提供的下游合成价值有限。本综述总结了勘探多重硼酸化烷烃的最新进展,包括关于如何在进一步的合成操作中详细阐述这些产品的讨论。