OBJECTIVE This study investigates the efficacy and feasibility of electrical stimulation (E-Stim) on sensory fibers of the plantar region during hemodialysis sessions, aiming to improve mobility in patients with diabetes by providing a connection between E-Stim and enhanced mobility with minimal patient effort required. RESEARCH DESIGN AND METHODS Participants age ≥18 years with diabetes undergoing hemodialysis and able to walk at least 10 m with or without aid were recruited and divided into an intervention group receiving 1-h intradialytic E-Stim three times a week and a control group using an identical nonfunctional device for 12 weeks. Gait, physical activity, patient-reported outcomes, and the technology acceptance model were assessed to evaluate the intervention’s effectiveness and acceptance. RESULTS Out of 117 initial participants, 97 completed the study. Significant improvements were observed in the intervention group compared with the control group in gait performance (stride time at dual-task and fast walking), physical activity (stand to walk and sit to stand), quality of life, plantar numbness, and cognitive function after 12 weeks. The intervention group showed that magnitudes of improvement on gait performance and physical activity metrics were associated with enhancements in quality of life and cognitive function, respectively. The intervention group also reported higher usefulness and usage satisfaction, with a greater willingness to continue using E-Stim at home. CONCLUSIONS The 12-week intradialytic E-Stim intervention is a feasible and effective method to enhance gait performance, physical activity level, cognitive function, and other patient-reported outcomes in patients undergoing hemodialysis, representing a practical, low-risk therapy option for those unable to engage in traditional exercise programs.

中文翻译：

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糖尿病患者透析中足底电刺激的有效性和可行性：随机双盲对照试验


目的 本研究调查了血液透析过程中电刺激 (E-Stim) 对足底感觉纤维的功效和可行性，旨在通过在 E-Stim 和增强活动能力之间建立联系，以最小的患者努力来改善糖尿病患者的活动能力必需的。研究设计和方法 招募年龄 ≥ 18 岁的糖尿病患者，接受血液透析，并且能够在有或没有帮助的情况下步行至少 10 m，并分为干预组，每周 3 次，接受 1 小时透析内 E-Stim 治疗，对照组则使用相同的无功能设备 12 周。对步态、体力活动、患者报告的结果和技术接受模型进行评估，以评估干预措施的有效性和接受度。结果 在 117 名初始参与者中，97 名完成了研究。与对照组相比，干预组在步态表现（双任务和快走的步幅时间）、体力活动（从站到走、从坐到站）、生活质量、足底麻木和认知功能方面都有显着改善12周后。干预组表明，步态表现和身体活动指标的改善程度分别与生活质量和认知功能的提高相关。干预组还报告了更高的实用性和使用满意度，并且更愿意继续在家使用 E-Stim。 结论 12 周透析中 E-Stim 干预是一种可行且有效的方法，可增强血液透析患者的步态表现、体力活动水平、认知功能和其他患者报告的结果，对于那些患者来说是一种实用的、低风险的治疗选择无法参加传统的锻炼计划。