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Venetoclax plus decitabine as a bridge to allogeneic haematopoietic stem-cell transplantation in older patients with acute myeloid leukaemia (VEN-DEC GITMO): final report of a multicentre, single-arm, phase 2 trial
The Lancet Haematology ( IF 15.4 ) Pub Date : 2024-09-20 , DOI: 10.1016/s2352-3026(24)00241-2 Prof Domenico Russo PhD, Nicola Polverelli PhD, Simona Bernardi PhD, Stella Santarone MD, Mirko Farina PhD, Erika Borlenghi MD, Francesco Onida MD, Luca Castagna MD, Stefania Bramanti MD, Angelo Michele Carella MD, Roberto Sorasio MD, Massimo Martino MD, Caterina Alati MD, Prof Attilio Olivieri MD, Germana Beltrami MD, Antonio Curti MD, Calogero Vetro MD, Salvatore Leotta MD, Valentina Mancini MD, Elisabetta Terruzzi MD, Massimo Bernardi MD, Piero Galieni MD, Prof Pellegrino Musto MD, Raffaella Cerretti MD, Luisa Giaccone MD, Cristina Skert MD, Vera Radici MD, Marika Vezzoli PhD, Prof Stefano Calza PhD, Alessandro Leoni MSc, Luca Garuffo MSc, Cristian Bonvicini PhD, Simone Pellizzeri MSc, Michele Malagola PhD, Prof Fabio Ciceri MD
The Lancet Haematology ( IF 15.4 ) Pub Date : 2024-09-20 , DOI: 10.1016/s2352-3026(24)00241-2 Prof Domenico Russo PhD, Nicola Polverelli PhD, Simona Bernardi PhD, Stella Santarone MD, Mirko Farina PhD, Erika Borlenghi MD, Francesco Onida MD, Luca Castagna MD, Stefania Bramanti MD, Angelo Michele Carella MD, Roberto Sorasio MD, Massimo Martino MD, Caterina Alati MD, Prof Attilio Olivieri MD, Germana Beltrami MD, Antonio Curti MD, Calogero Vetro MD, Salvatore Leotta MD, Valentina Mancini MD, Elisabetta Terruzzi MD, Massimo Bernardi MD, Piero Galieni MD, Prof Pellegrino Musto MD, Raffaella Cerretti MD, Luisa Giaccone MD, Cristina Skert MD, Vera Radici MD, Marika Vezzoli PhD, Prof Stefano Calza PhD, Alessandro Leoni MSc, Luca Garuffo MSc, Cristian Bonvicini PhD, Simone Pellizzeri MSc, Michele Malagola PhD, Prof Fabio Ciceri MD
Access to allogeneic haematopoietic stem-cell transplantation (HSCT) remains challenging for older patients (aged >60 years) with acute myeloid leukaemia. We aimed to evaluate the efficacy of venetoclax plus decitabine as first-line therapy and bridge to transplantation in this patient population.
中文翻译：
维奈托克加地西他滨作为老年急性髓性白血病患者同种异体造血干细胞移植的桥梁 （VEN-DEC GITMO）：一项多中心、单臂、2 期试验的最终报告
对于患有急性髓性白血病的老年患者 （年龄 >60 岁） 来说，获得同种异体造血干细胞移植 （HSCT） 仍然具有挑战性。我们旨在评估维奈托克联合地西他滨作为该患者群体一线治疗和移植过渡的疗效。
更新日期：2024-09-20
中文翻译：
维奈托克加地西他滨作为老年急性髓性白血病患者同种异体造血干细胞移植的桥梁 （VEN-DEC GITMO）：一项多中心、单臂、2 期试验的最终报告
对于患有急性髓性白血病的老年患者 （年龄 >60 岁） 来说，获得同种异体造血干细胞移植 （HSCT） 仍然具有挑战性。我们旨在评估维奈托克联合地西他滨作为该患者群体一线治疗和移植过渡的疗效。
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