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Role of Early On-Treatment Serum HBV RNA Declines in Predicting Hepatocellular Carcinoma Risk in Patients With Chronic Hepatitis B
Clinical Gastroenterology and Hepatology ( IF 11.6 ) Pub Date : 2024-08-23 , DOI: 10.1016/j.cgh.2024.07.024 Shi Liu, Grace Lai-Hung Wong, Rong Fan, Junqi Niu, Hong Ma, Wanying Liang, Xingyu Lu, Jianping Xie, Jia Shang, Dongying Xie, Yali Liu, Bin Zhou, Qing Xie, Jie Peng, Hongbo Gao, Huiying Rao, Jinjun Chen, Jifang Sheng, Sheng Shen, Song Yang, Xiaoguang Dou, Zhengang Zhang, Vincent Wai-Sun Wong, Jinlin Hou, Jian Sun
Clinical Gastroenterology and Hepatology ( IF 11.6 ) Pub Date : 2024-08-23 , DOI: 10.1016/j.cgh.2024.07.024 Shi Liu, Grace Lai-Hung Wong, Rong Fan, Junqi Niu, Hong Ma, Wanying Liang, Xingyu Lu, Jianping Xie, Jia Shang, Dongying Xie, Yali Liu, Bin Zhou, Qing Xie, Jie Peng, Hongbo Gao, Huiying Rao, Jinjun Chen, Jifang Sheng, Sheng Shen, Song Yang, Xiaoguang Dou, Zhengang Zhang, Vincent Wai-Sun Wong, Jinlin Hou, Jian Sun
Hepatocellular carcinoma (HCC) risk prediction models established in patients with chronic hepatitis B receiving a nucleos(t)ide analogue (NA) rarely include viral factors because of mediocre predictability of traditional viral markers. Here, we investigate the role of serum hepatitis B virus (HBV) RNA, a novel biomarker, in predicting HCC risk in NA-treated patients.
中文翻译:
早期治疗血清 HBV RNA 下降在预测慢性乙型肝炎患者肝细胞癌风险中的作用
由于传统病毒标志物的预测能力一般,在接受核苷(酸)类似物(NA)治疗的慢性乙型肝炎患者中建立的肝细胞癌(HCC)风险预测模型很少包括病毒因素。在这里,我们研究了血清乙型肝炎病毒 (HBV) RNA(一种新型生物标志物)在预测 NA 治疗患者的 HCC 风险中的作用。
更新日期:2024-08-23
中文翻译:
早期治疗血清 HBV RNA 下降在预测慢性乙型肝炎患者肝细胞癌风险中的作用
由于传统病毒标志物的预测能力一般,在接受核苷(酸)类似物(NA)治疗的慢性乙型肝炎患者中建立的肝细胞癌(HCC)风险预测模型很少包括病毒因素。在这里,我们研究了血清乙型肝炎病毒 (HBV) RNA(一种新型生物标志物)在预测 NA 治疗患者的 HCC 风险中的作用。