BACKGROUND In refractory cardiac arrest, extracorporeal cardiopulmonary resuscitation may increase the survival chance. However, in cases of unsuccessful treatment, extracorporeal cardiopulmonary resuscitation may additionally provide an important source of organ donors. Therefore, we hypothesized that implementing extracorporeal cardiopulmonary resuscitation service into a high-volume cardiac arrest center's routine would increases organ donors' availability. METHODS Our retrospective observational study analyzed out-of-hospital cardiac arrest patients admitted to the General University Hospital in Prague between 2007 and 2020. The following groups were analyzed regarding the recruitment of donors: before and after extracorporeal cardiopulmonary resuscitation implementation. We assessed the number of donors referred, the number of organs harvested, and the organ's survival. RESULTS We analyzed the results of 1,158 patients after out-of-hospital cardiac arrest. In the conventional approach period, 11 donors were referred, of which 7 were accepted. During the extracorporeal cardiopulmonary resuscitation period, the number of donors increased to 80, of whom 42 were accepted. The number of donated organs was 18 and 119 in the respective periods, corresponding to 3.6 vs 13.2 (p = 0.033) harvested organs per year. One-year survival of transplanted organs was 94.4% vs 99.2%, and 5-year survival was 94.4% vs 95.9% in relevant periods. Conventional and extracorporeal cardiopulmonary resuscitation did not affect donor organ survival. CONCLUSION Establishing a high-volume cardiac arrest center providing an extracorporeal cardiopulmonary resuscitation service may increase not only the number of prolonged cardiac arrest survivors but also the number of organ donors. In addition, the performances of donated organs were high and comparable between both treatment methods.

中文翻译：

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常规体外心肺复苏服务对供体器官可用性的影响。


背景 在难治性心脏骤停中，体外心肺复苏可能会增加生存机会。然而，在治疗不成功的情况下，体外心肺复苏可能还可能提供器官捐献者的重要来源。因此，我们假设将体外心肺复苏服务实施到大容量心脏骤停中心的常规工作中会增加器官捐献者的可用性。方法 我们的回顾性观察性研究分析了 2007 年至 2020 年间布拉格综合大学医院收治的院外心脏骤停患者。对以下组进行供体招募分析： 体外心肺复苏实施前后。我们评估了转诊的供体数量、摘取的器官数量以及器官的存活率。结果 我们分析了 1,158 例院外心脏骤停后患者的结果。在常规方法期间，推荐了 11 名供体，其中 7 名被接受。体外心肺复苏期，供体人数增加到 80 人，其中 42 人被接受。在相应时期，捐献的器官数量分别为 18 个和 119 个，相当于每年收获的器官数量为 3.6 对 13.2 （p = 0.033）。移植器官的 1 年生存率为 94.4% vs 99.2%，相关时期的 5 年生存率为 94.4% vs 95.9%。常规和体外心肺复苏不影响供体器官的存活。结论 建立提供体外心肺复苏服务的大容量心脏骤停中心不仅可能增加长时间心脏骤停幸存者的数量，还可能增加器官捐献者的数量。 此外，两种治疗方法的捐献器官性能较高且具有可比性。