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Synaptotagmin-1 in phase: Condensate biology reveals new insights into the synaptic calcium sensor.
Journal of Cell Biology ( IF 7.4 ) Pub Date : 2024-09-17 , DOI: 10.1083/jcb.202408073
Johannes Vincent Tromm 1 , Dragomir Milovanovic 1
Affiliation  

Two recent papers by Mehta et al. and Zhu et al. in this issue (https://doi.org/10.1083/jcb.202311191) discover that synaptotagmin-1, the primary calcium sensor at the synapse, forms biomolecular condensates, identifying a new layer of regulation in calcium-triggered synaptic vesicle exocytosis.

中文翻译:


Synaptotagmin-1 处于阶段:冷凝生物学揭示了对突触钙传感器的新见解。



Mehta 等人最近发表的两篇论文。和朱等人。在本期 (https://doi.org/10.1083/jcb.202311191) 中,我们发现突触的主要钙传感器 synaptotagmin-1 形成生物分子凝聚物,从而确定了钙触发的突触小泡胞吐作用的新调节层。
更新日期:2024-09-17
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