A series of 4‐aryl‐3‐methyl‐1‐phenyl‐7H‐furo[3,4‐e]pyrazolo[3,4‐b]pyridine‐5‐ones were synthesized via the three‐component reaction of an aldehyde, 5‐amino‐3‐methyl‐1‐phenyl‐1H‐pyrazole and tetronic acid in aqueous media in the presence of triethylbenzylammonium chloride (TEBAC). This method has the advantages of easier work‐up, mild reaction conditions, high yields, and an environmentally benign procedure. J. Heterocyclic Chem., (2009).

中文翻译：

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在水介质中清洁合成呋喃并[3,4-e]吡唑并[3,4-b]吡啶-5-酮衍生物

通过醛的三组分反应合成了一系列的4-芳基-3-甲基-1-苯基-7 H-呋喃[3,4- e ]吡唑并[3,4- b ]吡啶-5-酮，在三乙基苄基氯化铵（TEBAC）存在下，在水性介质中的5-氨基-3-甲基-1-苯基-1 H-吡唑和tetronic酸。该方法的优点是后处理容易，反应条件温和，收率高以及对环境无害。J.杂环化​​学，（2009）。