We read with great interest the study by O’Sullivan et al ,1 examining the technical and procedural outcomes of Cold Endoscopic Mucosal Resection (C-EMR) versus Hot EMR (H-EMR). We congratulate the authors for conducting this important research, which adds valuable information to the body of knowledge guiding our choice of the optimal treatment modality for large, benign colorectal polyps. However, we would like to address several points. First, readers should be aware that this study focuses on a highly selected group of large non-pedunculated colon polyps (LNPCPs) as only 20% of referred lesions during the study period of 4 years met the inclusion criteria, being flat lesions of 15–50 mm, without macronodule, depressed area or optical suspicion of submucosal invasive cancer (SMIC). Despite this selection, 2.2% unrecognised SMIC was found, …

中文翻译：

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用于大型良性腺瘤的冷 EMR、热 EMR 或 ESD：没有一种方法适合所有情况


我们饶有兴趣地阅读了 O'Sullivan 等人的研究1，该研究检查了冷内镜粘膜切除术 (C-EMR) 与热 EMR (H-EMR) 的技术和程序结果。我们祝贺作者进行了这项重要的研究，该研究为知识体系增添了宝贵的信息，指导我们选择大型良性结直肠息肉的最佳治疗方式。不过，我们想谈几点。首先，读者应该意识到，本研究重点关注一组经过精心挑选的大型无蒂结肠息肉 (LNPCP)，因为在 4 年的研究期间，只有 20% 的转介病变符合纳入标准，即 15-15 的扁平病变。 50毫米，无大结节、凹陷区或光学怀疑粘膜下浸润癌（SMIC）。尽管进行了这样的选择，还是发现了 2.2% 未被识别的中芯国际，……