Silencing the transcriptionally active HIV reservoir to improve treatment outcomes,Nature Microbiology

当前位置： X-MOL 学术 › Nat. Microbiol. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Silencing the transcriptionally active HIV reservoir to improve treatment outcomes
Nature Microbiology ( IF 20.5 ) Pub Date : 2024-09-17 , DOI: 10.1038/s41564-024-01816-5
Julia Prigann ₁ , Rubens Tavora _{2,

3} , Robert L Furler O'Brien _{1,

4,

5} , Ursula Schulze-Gahmen ₁ , Daniela Boehm ₁ , Nadia R Roan _{1,

6} , Douglas F Nixon _{4,

5} , Lishomwa C Ndhlovu ₅ , Susana Valente _{2,

3} , Melanie Ott _{1,

7}

Affiliation

Persistence of the transcriptionally active HIV reservoir has important implications for people living with HIV, including chronic immune activation and inflammation. Supplementing antiretroviral therapy with transcriptional inhibitors could overcome this by silencing the transcriptionally active HIV reservoir.

中文翻译：