To identify chemical-markers from hot-pressed, cold-pressed, organic-solvent, aqueous-enzymatic and water extracted camellia oils (HPO, CPO, OSO, AEO, WEO). We report a full composition-wide association study based on GC–MS, LC-MS and 1HNMR. Squalene, β-amyrin and lupeol were potential-markers in distinguishing different oils through GC–MS. Naringenin, FA 18:1 + 10, undecanedioic acid and tridecanedioic acid exhibited were up-regulated in HPO. 16-Hydroxyhexadecanoic acid, octadecanoic acid and 9-hydroxyoctadecadienoic acid were potential-metabolites in CPO. Characteristic-markers in WEO were hydroquinidine and undecanedioic acid. Gallic acid, hydroquinidine, lichesterylic acid and 7,4′-dihydroxyflavone were biomarkers in AEO. Oleic acid, linoleic acid and triacylglycerols may be potential key markers to distinguish AEO from others via 1HNMR. Finally, Naringenin, gallic acid, kaempferol, 7,4′-dihydroxyflavone, (Z)-5,8,11-trihydroxyoctadec-9-enoic acid and β-amyrin were screened and validate through integration of nonglyceride minor components and trace metabolites. Results provided understanding of chemical diversity for different processed-camellia oils, and proposed a complementary strategy to distinguish different camellia oils for multidimensional perspective.

中文翻译：

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完整的成分范围关联研究确定了区分不同加工山茶油的化学标志物：将多靶点与化学计量学相结合


鉴定热榨、冷榨、有机溶剂、水酶和水萃取山茶油（HPO、CPO、OSO、AEO、WEO）的化学标志物。我们报告了一项基于 GC-MS、LC-MS 和 1HNMR 的完整全成分关联研究。角鲨烯、β-胰液酸和羽扇豆醇是通过 GC–MS 区分不同油的潜在标志物。柚皮素、FA 18：1 + 10、十一烷二酸和十三烷二酸在 HPO 中上调。16-羟基十六烷酸、十八烷酸和 9-羟基十八碳二烯酸是 CPO 中的潜在代谢产物。WEO 中的特征标志物是氢奎尼丁和十一烷二酸。没食子酸、氢奎尼丁、柠檬酸和 7,4′-二羟基黄酮是 AEO 的生物标志物。油酸、亚油酸和三酰甘油可能是通过 1HNMR 区分 AEO 与其他物质的潜在关键标志物。最后，通过整合非甘油酯次要成分和痕量代谢物，筛选和验证柚皮素、没食子酸、山奈酚、7,4′-二羟基黄酮、（Z）-5,8,11-三羟基十八碳-9-烯酸和 β-胰蛋白酶。结果提供了对不同加工山茶油的化学多样性的理解，并提出了一种互补策略来区分不同的山茶油，以实现多维视角。