A simple synthesis of 5-(trifluoromethyl)cyclohexane-1,2,3-trione is demonstrated in one step, by reacting 5-(trifluoromethyl)cyclohexane-1,3-dione with cerium(IV)ammonium nitrate (CAN) in methanol. The compound represents a highly functionalized oxygen-rich reactive intermediate for the synthesis of organic and heterocyclic compounds containing fluorine.

中文翻译：

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5-（三氟甲基）环己烷-1,2,3-三酮（cVTC）的合成：新的三氟甲基构件

通过使5-（三氟甲基）环己烷-1,3-二酮与硝酸铈（IV）铵（CAN）在甲醇中反应，一步展示了5-（三氟甲基）环己烷-1,2-，3-三酮的简单合成。该化合物代表用于合成含氟有机和杂环化合物的高度官能化的富氧反应性中间体。