Significant volume is pooled in veins in humans and the amount is dramatically altered by various physiological stresses and diseases. Several animal and human studies demonstrated that limb venous distension evoked significant increases in blood pressure and sympathetic nerve activity (venous distension reflex, VDR). VDR has attracted much attention because of its potential to explain the still unknown mechanism of autonomic dysfunction in several diseases, which would lead to a new treatment approach. This mini review discusses accumulated evidence of VDR at this point and what should be investigated in the future to apply the current understanding of VDR in clinical practice.

中文翻译：

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外周静脉扩张反射在调节血流动力学中的作用：小型回顾


大量的体积在人类的静脉中汇集，并且其数量会因各种生理压力和疾病而发生巨大变化。几项动物和人类研究表明，肢体静脉扩张引起血压和交感神经活动 （静脉扩张反射，VDR） 的显着增加。VDR 因其可能解释几种疾病中仍然未知的自主神经功能障碍机制而引起广泛关注，这将导致一种新的治疗方法。本小型综述讨论了此时 VDR 的积累证据，以及未来应调查哪些内容以将当前对 VDR 的理解应用于临床实践。