Chitosan holds great promise for demanding applications such as functional packing and biomedical uses. There has been a notable increase in interest in combining chitosan or its derivatives with other polymers and nanofillers to achieve synergistic effects. Remarkable progress has been made through polymer molecular design and iterative nanotechnology in the development of chitosan-based nanocomposite materials tailored for high-performance applications. This review focuses on strategies to develop chitosan-based materials, highlighting the advantages and disadvantages of chitosan modification and critically evaluating various fabrication methods. Following a brief introduction to various nanofillers and their functionalization, this review discusses the functional properties (e.g., mechanical, thermal, water resistance, gas-barrier, stimulus-response, shape memory, biological, electrochemical, corrosion-protection, antifouling, and abruption/desorption) of various chitosan-based nanocomposite systems. It then highlights the emerging and potential applications of chitosan-based nanocomposites in various fields such as functional packaging, biomedicine, 3D bioprinting, sensing and wearable devices, environmental remediation, and chemical engineering. Moreover, we explore the factors that hinder the commercialization of chitosan-based nanocomposites. Our review not only surveys recent advancements in engineering sophisticated functional chitosan-based nanocomposite materials, customized for a diverse array of applications, but also offers insights into the future formulation of multifaceted chitosan-based nanocomposites, poised to tackle the distinct demands and hurdles encountered in burgeoning applications.

中文翻译：

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用于性能要求苛刻的先进功能性壳聚糖基纳米复合材料


壳聚糖在功能性包装和生物医学用途等要求苛刻的应用中前景广阔。人们越来越关注将壳聚糖或其衍生物与其他聚合物和纳米填料结合以实现协同效应。通过聚合物分子设计和迭代纳米技术，在开发为高性能应用量身定制的壳聚糖基纳米复合材料方面取得了显着进展。本文重点介绍壳聚糖基材料的开发策略，强调壳聚糖改性的优缺点，并批判性地评价各种制造方法。在简要介绍了各种纳米填料及其功能化之后，本文讨论了各种壳聚糖基纳米复合材料系统的功能特性（例如，机械、热、防水、气体屏障、刺激反应、形状记忆、生物、电化学、腐蚀保护、防污和早剥/解吸）。然后，它重点介绍了壳聚糖基纳米复合材料在功能包装、生物医学、3D 生物打印、传感和可穿戴设备、环境修复和化学工程等各个领域的新兴和潜在应用。此外，我们探讨了阻碍壳聚糖基纳米复合材料商业化的因素。我们的综述不仅调查了为各种应用定制的复杂功能性壳聚糖基纳米复合材料工程的最新进展，而且还为多方面壳聚糖基纳米复合材料的未来配方提供了见解，以应对新兴应用中遇到的不同需求和障碍。