N-terminal pro–B-type natriuretic peptides (NT-proBNPs) are guideline-recommended biomarkers for risk stratification in patients with heart failure. However, NT-proBNP levels are often elevated in chronic kidney disease, introducing uncertainty about their prognostic relevance in persons across a broad range of estimated glomerular filtration rate (eGFR).

中文翻译：

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利钠肽、肾功能和射血分数保留心力衰竭的临床结果


N 末端 pro-B 型利钠肽 （NT-proBNPs） 是指南推荐的心力衰竭患者风险分层的生物标志物。然而，NT-proBNP 水平在慢性肾病患者中通常会升高，这导致它们在估计肾小球滤过率 （eGFR） 范围内的个体预后相关性存在不确定性。