It is imperative to develop non-enzyme testing techniques that are convenient and accurate for early diagnosis of diabetes. This study designed and synthesized a novel heterogeneous transition bimetallic chalcogenide compound (10-X)NiS2@XCuS using a simple one-step hydrothermal method. The self-assembly process of the core–shell structure was verified and scrutinized via transmissionelectronmicroscopyandex-situX-raydiffraction. By optimizing reaction conditions and elemental ratios, well-dispersed flower-like NiS2@CuS nanocomposites were successfully synthesized, exhibiting a significantly enhanced specific surface area and electronic activity of the particles. Subsequent evaluation of a glass carbon electrode modified with NiS2@CuS revealed promising glucose detection performance. The results showcase an expansive linear detection range spanning from 1 μmol/L to 12 mmol/L for glucose, coupled with remarkable sensitivity (5876.8 μA mM−1 cm−2), robust anti-interference capabilities, and excellent stability, outperforming most existing non-enzymatic glucose detection methods. Moreover, based on these findings, an accurate and user-friendly portable glucose detection system has been developed to ensure precise monitoring of glucose levels.

中文翻译：

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基于异质自组装NiS2@CuS核壳纳米复合材料的非酶葡萄糖传感器电极及便携式检测系统设计


当务之急是开发方便、准确的非酶检测技术，以便于糖尿病的早期诊断。本研究使用简单的一步水热法设计合成了一种新的非均相过渡双金属硫属化物化合物 （10-X NiS2@XCuS。通过透射电子显微镜和原位X射线衍射验证和审查了核壳结构的自组装过程。通过优化反应条件和元素比例，成功合成了分散良好的花状NiS2@CuS纳米复合材料，表现出显着增强的粒子比表面积和电子活性。随后对 NiS2@CuS 改性的玻璃碳电极的评估显示出有希望的葡萄糖检测性能。结果展示了葡萄糖的宽线性检测范围，范围从 1 μmol/L 到 12 mmol/L，加上显着的灵敏度 （5876.8 μA mM-1 cm-2）、强大的抗干扰能力和出色的稳定性，优于大多数现有的非酶葡萄糖检测方法。此外，基于这些发现，已经开发了一种准确且用户友好的便携式血糖检测系统，以确保精确监测血糖水平。