Nanotechnology-based approaches for antibacterial therapy,European Journal of Medicinal Chemistry

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Nanotechnology-based approaches for antibacterial therapy
European Journal of Medicinal Chemistry ( IF 6.0 ) Pub Date : 2024-08-27 , DOI: 10.1016/j.ejmech.2024.116798
Siyuan Dong ₁ , Xi Li ₂ , Qi Pan ₃ , Kangchun Wang ₄ , Ning Liu ₅ , Wang Yutao ₆ , Yijie Zhang ₃

Affiliation

The technique of antimicrobial therapy action is to stop or slow the growth of bacteria that can kill people, animals, and crops. The most widely used antibacterial agents are antibiotics. Even though these antimicrobial medications are quite effective, there are still certain barriers or challenges in using them effectively. To solve these issues, new antimicrobial drug molecules that don't have side effects or resistance are needed. These days, antimicrobial drugs placed in nanosized vehicles, or nanomedicine, made of different metal and metallic oxides as well as of polymer, carbon or lipid-based may be used to address these issues with conventional therapy and delivery techniques. This review focuses on the importance of nanotechnology in antimicrobial therapy, nanoparticles (NPs) used in this therapy, their mode of action, and the recent advancement in nanotechnology for antimicrobial therapy.

中文翻译：

基于纳米技术的抗菌治疗方法

抗菌治疗作用的技术是阻止或减缓可以杀死人、动物和农作物的细菌的生长。使用最广泛的抗菌剂是抗生素。尽管这些抗菌药物非常有效，但在有效使用它们方面仍然存在一定的障碍或挑战。为了解决这些问题，需要没有副作用或耐药性的新型抗菌药物分子。如今，放置在纳米载体中的抗菌药物或纳米药物，由不同的金属和金属氧化物以及聚合物、碳或脂质基制成，可用于通过常规治疗和输送技术解决这些问题。本综述重点介绍纳米技术在抗菌治疗中的重要性、该疗法中使用的纳米颗粒（NPs）、它们的作用方式以及纳米技术在抗菌治疗中的最新进展。

更新日期：2024-08-27

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