Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) is an autoimmune process resulting in painful epidermal sloughing that can involve the vulva and vagina. Current guideline recommendations are based on expert opinion and may not reflect modern management of SJS/TEN in burn centers. We performed a retrospective chart review of 34 female patients treated for SJS/TEN at our burn center from 2015 to 2023. Cases frequently involved the vulva (83.3%) and vagina (56.0%), though pelvic examination often was limited. For eight patients with confirmed vulvovaginal lesions, there were no direct sequelae of SJS/TEN requiring intervention. In the modern era of SJS/TEN management in burn centers, interventions such as steroids may not be needed.

中文翻译：

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外阴阴道史蒂文斯-约翰逊综合征和中毒性表皮坏死松解症的治疗。


史蒂文斯-约翰逊综合征和中毒性表皮坏死松解症 (SJS/TEN) 是一种自身免疫过程，会导致痛苦的表皮脱落，并可能累及外阴和阴道。目前的指南建议基于专家意见，可能无法反映烧伤中心 SJS/TEN 的现代管理。我们对 2015 年至 2023 年在我们烧伤中心接受 SJS/TEN 治疗的 34 名女性患者进行了回顾性图表回顾。病例经常累及外阴 (83.3%) 和阴道 (56.0%)，尽管盆腔检查常常受到限制。对于 8 名确诊外阴阴道病变的患者，没有出现需要干预的 SJS/TEN 直接后遗症。在烧伤中心 SJS/TEN 管理的现代时代，可能不需要类固醇等干预措施。