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Postprandial metabolomics analysis reveals disordered serotonin metabolism in post-bariatric hypoglycemia
The Journal of Clinical Investigation ( IF 13.3 ) Pub Date : 2024 , DOI: 10.1172/jci180157
Rafael Ferraz-Bannitz 1 , Berkcan Ozturk 1 , Cameron J Cummings 1 , Vissarion Efthymiou 1 , Pilar Casanova Querol 1 , Lindsay Poulos 1 , Hanna J Wang 1 , Valerie Navarrete 1 , Hamayle Saeed 1 , Christopher M Mulla 1 , Hui Pan 1 , Jonathan M Dreyfuss 1 , Donald C Simonson 2 , Darleen A Sandoval 3 , Mary-Elizabeth Patti 1
Affiliation  

BACKGROUND. Bariatric surgery is a potent therapeutic approach for obesity and type 2 diabetes but can be complicated by post-bariatric hypoglycemia (PBH). PBH typically occurs 1–3 hours after meals, in association with exaggerated postprandial levels of incretins and insulin.

中文翻译:


餐后代谢组学分析显示减重后低血糖症中 5-羟色胺代谢紊乱



背景。 减重手术是治疗肥胖和 2 型糖尿病的有效方法,但可能会因减重后低血糖 (PBH) 而复杂化。PBH 通常发生在饭后 1-3 小时,与餐后肠促胰岛素和胰岛素水平升高有关。
更新日期:2024-11-02
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