One step at a time: new insights into double-stranded ribonucleic acid virus assembly,Signal Transduction and Targeted Therapy

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One step at a time: new insights into double-stranded ribonucleic acid virus assembly
Signal Transduction and Targeted Therapy ( IF 40.8 ) Pub Date : 2024-09-13 , DOI: 10.1038/s41392-024-01949-3
Virgile Rat ₁ , Alexander Borodavka ₂ , Don C Lamb ₁

Affiliation

In a recent paper published in Cell, Xia et al.¹ carried out 3D reconstructions of Blue Tongue Virus (BTV) particles and their assembly intermediates using a combination of cellular cryo-electron tomography (Cryo-ET) and single-particle cryo-electron microscopy (Cryo-EM). They were able to identify 11 structures, allowing them to refine our understanding of how double-stranded ribonucleic acid (dsRNA) viruses replicate in cells.

中文翻译：

一步一个脚印：双链核糖核酸病毒组装的新见解

在最近发表在《细胞》上的一篇论文中，Xia 等人1 使用细胞冷冻电子断层扫描（Cryo-ET）和单颗粒冷冻电子显微镜（Cryo-EM） ^{的组合，对}蓝舌病毒（BTV）颗粒及其组装中间体进行了 3D 重建。他们能够识别出 11 种结构，使他们能够完善我们对双链核糖核酸（dsRNA）病毒如何在细胞中复制的理解。

更新日期：2024-09-13

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