Plasma levels of the catecholamine norepinephrine (NE) has emerged as a useful tool to help differentiate pre- and post-ganglionic disorders in patients with cardiovascular autonomic failure (AF). However, data on intrasubject reliability in individuals with these conditions are limited. We evaluated the intrasubject reproducibility of supine plasma NE levels drawn across two consecutive time points under controlled conditions during head-up table testing in a large cohort of patients with alpha-synucleinopathies and both pre- and post-ganglionic cardiovascular AF.

中文翻译：

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心血管交感神经衰竭患者仰卧位去甲肾上腺素血浆浓度的受试者内重现性


儿茶酚胺去甲肾上腺素 （NE） 的血浆水平已成为帮助区分心血管自主神经衰竭 （AF） 患者神经节前后疾病的有用工具。然而，关于患有这些情况的个体的受试者内可靠性的数据是有限的。在一大群 α-突触核蛋白病和神经节前后心血管 AF 患者中，我们评估了在受控条件下连续两个时间点绘制的仰卧位血浆 NE 水平的受试者内重现性。