This special issue on autologous platelet concentrates (APCs) provides clinicians with an overview on the current understanding of the use of these biomaterials for soft and hard‐tissue regeneration. The included papers summarize scientific evidence and the clinical findings, presented in simple tables that outline potential benefits including Patient Reported Outcome Measures (PROMs). This approach enables clinicians to assess clinical relevance and researchers to identify significant gaps in the literature. The first part provides a comprehensive summary of the basic science surrounding APC, with particular focus on their preparation methods. Clear recommendations are outlined, which are crucial for obtaining high‐quality APCs, alongside an exploration of how APCs may influence both soft and hard tissue healing processes. Part 2 delves into the clinical evidence for the potential benefits of APCs across a range of applications: alveolar ridge preservation, sinus floor elevation, periodontal plastic surgery, guided tissue regeneration, guided bone regeneration, the healing of Medication‐Related Osteonecrosis of the Jaw (MRONJ), and endodontic surgery. In the part 3, the discussion turns to the effects of APCs on the healing of extra‐oral wounds, including diabetic foot ulcers, venous leg ulcers, pressure injuries, burns, and more. For those clinicians persuaded by the evidence, the fourth section offers a detailed, step‐by‐step flowchart for each treatment modality, providing a clear guide for clinical application.

中文翻译：

---

自体血小板浓缩液简介和概述


本期关于自体血小板浓缩物 (APC) 的特刊为临床医生提供了对这些生物材料用于软组织和硬组织再生的当前理解的概述。所包含的论文总结了科学证据和临床发现，并以简单的表格形式呈现，概述了潜在的益处，包括患者报告的结果测量 (PROM)。这种方法使临床医生能够评估临床相关性，并使研究人员能够识别文献中的重大差距。第一部分全面总结了 APC 的基础科学，特别关注其制备方法。概述了对于获得高质量 APC 至关重要的明确建议，同时还探索了 APC 如何影响软组织和硬组织愈合过程。第 2 部分深入探讨了 APC 在一系列应用中潜在益处的临床证据：牙槽嵴保存、窦底抬高、牙周整形手术、引导组织再生、引导骨再生、药物相关颌骨坏死的愈合（ MRONJ）和牙髓手术。在第三部分中，讨论转向 APC 对口外伤口愈合的影响，包括糖尿病足溃疡、腿部静脉溃疡、压力性损伤、烧伤等。对于那些被证据说服的临床医生，第四部分为每种治疗方式提供了详细的分步流程图，为临床应用提供了明确的指南。