AimAs data are sparse on the long‐term association between periodontal diseases and development of metabolic syndrome (MetS), we investigated their relationship in a Thai cohort over a 10‐year observational period.MethodsMedical records and data on periodontal assessments of 2161 employees of the Electricity Generating Authority of Thailand collected at two time points, 2003 and 2013, were used. Experienced periodontists used standard national and international criteria to define periodontitis and MetS. The impact of baseline periodontitis on subsequent MetS incidence and its components was evaluated using regression analyses.ResultsThe severity and extent of periodontitis significantly predicted MetS incidence over a decade, with a higher incidence of MetS in individuals with poorer periodontal health. A single percentage increase in the periodontitis extent raised the risk of MetS incidence by 0.4% and the risk of developing individual components of MetS by 0.2%. Independent of periodontal health, age of an individual emerged as a factor impacting MetS development.ConclusionThis study highlights the potential effect of the severity and extent of periodontitis on the increased incidence and progression of MetS. Hyperglycaemia and hypertension were the two MetS components most significantly affected by the existence of periodontitis.

中文翻译：

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牙周病对代谢综合征发展的潜在影响：泰国成人队列的 10 年观察研究


由于关于牙周病与代谢综合征 (MetS) 之间长期关联的数据很少，我们在泰国队列中进行了为期 10 年的观察期研究。方法 医疗记录和牙周评估数据对 2161 名员工进行了研究使用泰国发电局在 2003 年和 2013 年两个时间点收集的数据。经验丰富的牙周病专家使用标准的国家和国际标准来定义牙周炎和 MetS。使用回归分析评估基线牙周炎对随后 MetS 发生率及其组成部分的影响。结果牙周炎的严重程度和范围显着预测了十年内 MetS 的发生率，牙周健康状况较差的个体中 MetS 的发生率较高。牙周炎程度每增加一个百分比，MetS 发生风险就会增加 0.4%，而发生 MetS 个别成分的风险就会增加 0.2%。与牙周健康无关，个体年龄成为影响 MetS 发展的一个因素。结论本研究强调了牙周炎的严重程度和范围对 MetS 发病率和进展增加的潜在影响。高血糖和高血压是受牙周炎影响最显着的两个 MetS 成分。