This guideline was developed according to the British Society for Rheumatology Guidelines Protocol by a Guideline Development Group comprising healthcare professionals with expertise in SSc and people with lived experience, as well as patient organization representatives. It is an update of the previous 2015 SSc guideline. The recommendations were developed and agreed by the group and are underpinned by published evidence, assessed by systematic literature review and reinforced by collective expert opinion of the group. It considers all aspects of SSc including general management, treatment of organ-based complications, including cardiopulmonary, renal and gastrointestinal tract manifestations, as well as broader impact of disease. Whilst it is focused on adults with SSc we expect that the guideline will be relevant to people of all ages and expert input and review by paediatric rheumatologists and other relevant specialists considered where the guideline was, or may not be, applicable to young people with SSc and juvenile-onset disease. In addition to providing guidance on disease assessment and management the full guideline also considers service organization within the National Health Service and future approaches to audit of the guideline. The lay summary that accompanies this abstract can be found in Supplemental information 1.

中文翻译：

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2024 年英国风湿病学会系统性硬化症管理指南——执行摘要


该指南由指南制定小组根据英国风湿病学会指南方案制定，该小组由具有 SSc 专业知识的医疗保健专业人员和具有生活经验的人员以及患者组织代表组成。它是对之前的 2015 SSc 指南的更新。这些建议由小组制定和同意，并以已发表的证据为基础，通过系统的文献综述进行评估，并得到小组集体专家意见的强化。它考虑了 SSc 的所有方面，包括一般管理、器官并发症的治疗，包括心肺、肾脏和胃肠道表现，以及疾病的更广泛影响。虽然该指南侧重于成人 SSc，但我们预计该指南将适用于所有年龄段的人群，并由儿科风湿病学家和其他相关专家提供专家意见和审查，这些专家认为该指南适用于或可能不适用于患有 SSc 和青少年发病的年轻人。除了提供疾病评估和管理方面的指导外，完整指南还考虑了国家卫生服务体系内的服务组织以及未来审核指南的方法。本摘要随附的简明摘要可在补充信息 1 中找到。