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The methodological and ethical concerns of genetic studies of same-sex sexual behavior
American Journal of Human Genetics ( IF 8.1 ) Pub Date : 2024-09-09 , DOI: 10.1016/j.ajhg.2024.08.007 Christa Ventresca 1 , Daphne O Martschenko 2 , Robbee Wedow 3 , Mete Civelek 4 , James Tabery 5 , Jedidiah Carlson 6 , Stephen C J Parker 7 , Paula S Ramos 8
American Journal of Human Genetics ( IF 8.1 ) Pub Date : 2024-09-09 , DOI: 10.1016/j.ajhg.2024.08.007 Christa Ventresca 1 , Daphne O Martschenko 2 , Robbee Wedow 3 , Mete Civelek 4 , James Tabery 5 , Jedidiah Carlson 6 , Stephen C J Parker 7 , Paula S Ramos 8
Affiliation
Same-sex sexual behavior has long interested genetics researchers in part because, while there is evidence of heritability, the trait as typically defined is associated with fewer offspring. Investigations of this phenomenon began in the 1990s with linkage studies and continue today with the advent of genome-wide association studies. As this body of research grows, so does critical scientific and ethical review of it. Here, we provide a targeted overview of existing genetics studies on same-sex sexual behavior, highlight the ethical and scientific considerations of this nascent field, and provide recommendations developed by the authors to enhance social and ethical responsibility.
中文翻译:
同性性行为遗传学研究的方法论和伦理问题
长期以来,遗传学研究人员一直对同性性行为感兴趣,部分原因是,虽然有证据表明存在遗传性,但通常定义的特征与较少的后代有关。对这种现象的研究始于 1990 年代的连锁研究,并随着全基因组关联研究的出现而继续进行。随着这一研究机构的增长,对其进行批判性的科学和伦理审查也随之发展。在这里,我们对现有的同性性行为遗传学研究进行了有针对性的概述,强调了这一新兴领域的伦理和科学考虑,并提供了作者为加强社会和道德责任而提出的建议。
更新日期:2024-09-09
中文翻译:
同性性行为遗传学研究的方法论和伦理问题
长期以来,遗传学研究人员一直对同性性行为感兴趣,部分原因是,虽然有证据表明存在遗传性,但通常定义的特征与较少的后代有关。对这种现象的研究始于 1990 年代的连锁研究,并随着全基因组关联研究的出现而继续进行。随着这一研究机构的增长,对其进行批判性的科学和伦理审查也随之发展。在这里,我们对现有的同性性行为遗传学研究进行了有针对性的概述,强调了这一新兴领域的伦理和科学考虑,并提供了作者为加强社会和道德责任而提出的建议。