Chemotherapy is associated with the induction of intestinal microbiota dysbiosis and gastrointestinal injuries. In this Cell Host & Microbe issue, Anderson et al. demonstrate that chemotherapy-induced epithelial cell apoptosis drives microbiota imbalance and transcriptional rewiring, which in turn delays intestinal recovery.

中文翻译：

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宿主和肠道微生物群之间的对话揭示了化疗的“灵丹妙药”治疗方案


化疗与肠道菌群失调和胃肠道损伤的诱导有关。在这个细胞宿主与微生物问题中，安德森等人证明了化疗诱导的上皮细胞凋亡驱动微生物群失衡和转录重新布线，这反过来又会延迟肠道恢复。