Breastfeeding provides infection protection for several pathogens but not for noroviruses. Mechanisms explaining this discrepancy have been unclear. In this issue of Cell Host & Microbe, Peiper et al. demonstrate that while breastmilk protects mice from intestinal damage, it promotes neonatal murine norovirus infection due to maternal-derived bile acids.1

中文翻译：

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有胆汁吗？母乳胆汁酸影响诺如病毒感染


母乳喂养为多种病原体提供感染保护，但不能为诺如病毒提供感染保护。解释这种差异的机制尚不清楚。在本期的Cell Host & Microbe中，Peiper等人展示了虽然母乳可以保护小鼠免受肠道损伤，但由于母源性胆汁酸，它会促进新生儿鼠诺如病毒感染。