During opportunistic pathogenic episodes, Candida albicans employs classical strategies such as the yeast-to-hyphae transition and immunogenic masking. In this issue of Cell Host & Microbe, Luo et al. unveil that the effector protein Cmi1 can be translocated into host cells and targets TBK1, thereby negatively regulating the host’s antifungal immune responses.

中文翻译：

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白色念珠菌逃避宿主免疫的隐身策略


在机会性致病性发作期间，白色念珠菌采用经典策略，例如酵母到菌丝的转变和免疫原性掩蔽。在本期的Cell Host & Microbe中，Luo等人揭示了效应蛋白Cmi1可以转移到宿主细胞中并靶向TBK1，从而负向调节宿主的抗真菌免疫反应。