RNA G-quadruplexes are dynamically regulated during stress and infection. In this issue of Cell Host & Microbe, Schult et al.1 demonstrate that an RNA G-quadruplex conserved across orthoflaviviruses binds hnRNPH1 to mitigate the host stress response, highlighting the potential of this dynamic proviral RNA structure as a pan-flaviviral target.

中文翻译：

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压力较小：病毒掌握 RNA G 四链体


RNA G 四链体在应激和感染期间受到动态调节。在本期的Cell Host & Microbe中，Schult等人1证明了在直黄病毒中保守的RNA G-四链体结合hnRNPH1以减轻宿主应激反应，突出了这种动态前病毒RNA结构作为泛黄病毒目标的潜力。